27
Mar

HIV treatment of adolescents in Myanmar

Peer reviewed research on HIV in Myanmar is still too rare.

Here is a paper on treatment of adolescents in Myanmar. And it is not paywalled.

Jamie

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High levels of viral repression, malnutrition and second-line ART use in adolescents living with HIV: a mixed methods study from Myanmar

Jillian Murray, Katherine Whitehouse, Janet Ousley, Elkin Bermudez, Theint Thida Soe, Adelene Hilbig, Kyi Pyar Soe, Phyu Ei Mon, Kyaw Tint Tun, Win Le Shwe Sin Ei, Joanne Cyr, Carole Deglise & Iza Ciglenecki

BMC Infectious Diseases volume 20, Article number: 241 (2020) Cite this article

Abstract
Background
Adolescents living with HIV/AIDS (ALHIV) are a particularly vulnerable but often overlooked group in the HIV response despite additional disease management challenges.

Methods
All ALHIV (10–19 years), on ART for ≥6 months, presenting to care at a Médecins Sans Frontières (MSF) clinic in Myanmar from January–April 2016 were eligible for the quantitative study component (clinical history, medical examination, laboratory investigation). A subset of these respondents were invited to participate in qualitative interviews. Interviews and focus groups were also conducted with other key informants (care givers, clinicians).

Results
Of 177 ALHIV, 56% (100) were aged 9–13 years and 77 (44%) were 14–19. 49% (86) had been orphaned by one parent, and 19% (33) by both. 59% (104) were severely underweight (BMI < 16). 47% presented with advanced HIV (WHO stage III/IV). 93% were virally supressed (< 250 copies/mL). 38 (21%) of ALHIV were on a second-line ART after first-line virological failure. Qualitative interviewing highlighted factors limiting adherence and the central role that HIV counsellors play for both ALHIV patients and caregivers. Conclusions Our study shows good clinical, immunological, and virological outcomes for a cohort of Myanmar adolescents living with HIV, despite a majority being severely underweight, presenting with Stage III or IV illness, and the prevalence of comorbid infections (TB). Many treatment and adherence challenges were articulated in qualitative interviewing but emphasized the importance of actively engaging adolescents in their treatment. Comprehensive HIV care for this population must include routine viral load testing and social support programs. https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-020-04968-x#article-info

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