Screening and treating for malaria and mass preventive therapy for tuberculosis have taken a bit of a beating lately. Here are two articles showing that some kinds of interventions don't work.

HIV is exceptional. Again.

Jamie

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The Failure of Screening and Treating as a Malaria Elimination Strategy
http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001595

A Trial of Mass Isoniazid Preventive Therapy for Tuberculosis Control
http://www.nejm.org/doi/full/10.1056/NEJMoa1214289